Lena Amend

This study shows that Prevotella intestinalis induces arthritis in resistant mice by activating intestinal immune cells and promoting Th17 differentiation through IL-6.

This study shows that inhibiting polysaccharide breakdown in Bacteroides thetaiotaomicron reduces cross-feeding and growth of Salmonella Typhimurium in mice.

The paper identifies gut microbiota-derived histamine as a factor enabling the CNS to suppress peripheral inflammation in RA by activating H3R in the intestine and modulating microglia.

The paper establishes a publicly available collection of 340 human gut bacterial strains, including 29 newly described species, and identifies plasmids and megaplasmids within these isolates.

This study identifies a small RNA, SrcF, essential for gut colonization of Segatella copri, regulated by complex carbohydrates and influenced by the human microbiome.

The paper compares microbiome composition and function across rheumatic diseases to identify microbial signatures predicting methotrexate response in RA and PsA.