Network analysis reveals strain-dependent response to misfolded tau aggregates
Dominic J. Acri, Yanwen You, Mason Douglas Tate, Hande Karahan, Pablo Martínez, Brianne McCord, Ahmad Daniel Sharify, Sutha K. John, Byung-Wook Kim, Luke Child Dabin, Stéphanie Philtjens, H. R. Sagara Wijeratne, Tyler J. McCray, Daniel C. Smith, Stephanie J. Bissel, , Jungsu Kim
The paper investigates how genetic background affects tau aggregate seeding in mice by analyzing RNA-seq and tau seeding activity data from four strains.
The Journal of Experimental Medicine · Jul 28, 2023Peer-reviewedNeuroscience