Author

Laura Petersilie

Heinrich Heine University DüsseldorfORCID 0000-0003-0888-101XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Christine R. RoseiD· 2 shared Agnieszka Rybak‐WolfiD· 1 shared Alessandro PrigioneiD· 1 shared Alok BhattaraiiD· 1 shared Andrea Rossi· 1 shared Andrea ZalianiiD· 1 shared Annette Seibt· 1 shared Annika WittichiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

Christine R. RoseORCID

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2 papers

Recent·Most cited

A Deep Learning-Based Segmentation of Cells and Analysis (DL-SCAN)

Alok Bhattarai, Jan Meyer, Laura Petersilie, Syed Islamuddin Shah, Louis A. Neu, Christine R. Rose, Ghanim Ullah

DL-SCAN automates cell segmentation and analysis in fluorescence microscopy images, improving consistency and reducing user bias in ion dynamics studies.

Biomolecules · Oct 23, 2024Peer-reviewedNeuroscience

Deep learning-driven neuromorphogenesis screenings identify repurposable drugs for mitochondrial disease

Carmen Menacho, Satoshi Okawa, Iris Álvarez‐Merz, Annika Wittich, Mikel Muñoz‐Oreja, Paweł Lisowski, Tancredi Massimo Pentimalli, Agnieszka Rybak‐Wolf, Gizem Inak, Shiri Zakin, Mathuravani A. Thevandavakkam, Laura Petersilie, Andrea Zaliani, Barbara Mlody, Annette Seibt, , Alessandro Prigione

The paper identifies repurposable drugs for mitochondrial disease by using deep learning to screen for compounds that improve neuronal commitment and neurogenesis in Leigh syndrome organoids.

bioRxiv · Jul 8, 2024 · PreprintNeuroscience