Jessica P. Roberts

SenCat catalogs senescence markers across 14 human cell types using transcriptomic and proteomic profiling, revealing shared metabolic pathways and enabling machine learning-based identification of senescent cells.

ProtPipe is a data analysis pipeline for proteomics and peptidomics that automates processing, quality control, and downstream analysis of mass spectrometry data.

The paper shows that loss of TDP-43 function leads to the expression of de novo proteins from mis-spliced mRNA transcripts in ALS/FTD.

This paper investigates how the G34S mutation in δ-catenin causes loss of function leading to social dysfunction in ASD by altering glutamatergic activity and GSK3β-mediated degradation.

This study shows that phosphorylation of GluA1 at S845 reduces AP2 binding, decreasing AMPAR endocytosis and increasing surface expression during synaptic plasticity.