Author

Meta Heidenreich

Consejo Superior de Investigaciones CientíficasORCID 0000-0002-2095-830XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Synthetic Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metagenomics· 1 Research Focus:protein design· 1 Assay:protein structure· 1

Frequent Co-Authors

Emmanuel D. LevyiD· 3 shared Arseniy A. LoboviD· 1 shared Avital Steinberg· 1 shared Ayala ShiberiD· 1 shared Benjamin DubreuiliD· 1 shared David Sriker· 1 shared Emanuele LocatelliiD· 1 shared Eyal ShimoniiD· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersSystems Biology

Emmanuel D. LevyORCID

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Author profile →

3 papers

Recent·Most cited

Structural determinants of co-translational protein complex assembly

Saurav Mallik, Johannes Venezian, Arseniy A. Lobov, Meta Heidenreich, Hector Garcia‐Seisdedos, Todd O. Yeates, Ayala Shiber, Emmanuel D. Levy

The paper identifies structural determinants of co-translational protein complex assembly and shows how intertwined subunits require synchronized proteostasis, with implications for protein stability and mRNA localization.

Cell · Dec 20, 2024Peer-reviewedSystems Biology

The phase separation landscape of genome-wide genetic perturbations

Meta Heidenreich, Saurabh Mathur, Tong Shu, Ying Xie, David Sriker, Benjamin Dubreuil, Liam J. Holt, Emmanuel D. Levy

The paper identifies 68 yeast genes that globally influence protein phase separation through genetic knockouts and synthetic biology.

bioRxiv · Oct 25, 2024 · PreprintCell Biology

Designer protein assemblies with tunable phase diagrams in living cells

Meta Heidenreich, Joseph M. Georgeson, Emanuele Locatelli, Lorenzo Rovigatti, Saroj Kumar Nandi, Avital Steinberg, Yotam Nadav, Eyal Shimoni, Samuel A. Safran, Jonathan P. K. Doye, Emmanuel D. Levy

The paper designs proteins that form tunable assemblies in cells and maps their phase diagrams to understand how interactions influence mesoscale structures.

Nature Chemical Biology · Jul 13, 2020Peer-reviewedSynthetic Biology