Cancer BiologybioRxivPreprint
Ovarian Tumor FAK Inhibition Releases Omega-3 Fatty Acids Stimulating GATA6 Peritoneal Macrophage CXCL13 Production Enhancing Immunotherapy
Xiao Lei Chen, Kevin M. Tharp, Marjaana Ojalill…·David D. Schlaepfer
This study shows FAK inhibition in ovarian tumors increases macrophage CXCL13 production via omega-3 fatty acids, enhancing B cell infiltration and immunotherapy response.