Author
University of California San DiegoORCID 0000-0001-7998-9963Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Xiao Lei Chen, Kevin M. Tharp, Marjaana Ojalill…·David D. Schlaepfer
This study shows FAK inhibition in ovarian tumors increases macrophage CXCL13 production via omega-3 fatty acids, enhancing B cell infiltration and immunotherapy response.
Xiao Lei Chen, Marjaana Ojalill, Christine Jean…·David D. Schlaepfer
The paper shows that deleting FAK in endothelial cells of PYK2-null mice activates p53, suppresses tumor growth, and limits metastasis, while FAK inhibition has different effects.
Jian Tang, Xian Jia, Taoling Zeng…·Guo Fu
This study shows Themis regulates T cell exhaustion by controlling TCR and PD-1 signaling, with loss of Themis causing severe immunopathology in chronic viral infection.