Author

Emma V. Jones

Medicines Discovery CatapultORCID 0000-0002-2114-8501Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

Frequent Co-Authors

Catherine B. LawrenceiD· 1 shared Charles W. BourqueiD· 1 shared Christopher HoyleiD· 1 shared Christopher K. SalmoniD· 1 shared Claire GizowskiiD· 1 shared David BroughiD· 1 shared David StellwageniD· 1 shared Emily McMahon· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Catherine B. LawrenceORCID

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2 papers

Recent·Most cited

Brazilin is a Natural Product Inhibitor of the NLRP3 Inflammasome

Emily McMahon, Sherihan El‐Sayed, Jack Green, Christopher Hoyle, Lorna M. FitzPatrick, Emma V. Jones, Eve Corrie, Rebecca L. Kelly, Mairi Challinor, Sally Freeman, Richard A. Bryce, Catherine B. Lawrence, David Brough, Paul R. Kasher

This study identifies brazilin as a natural product inhibitor of the NLRP3 inflammasome, effective in multiple models and suggesting its potential as a therapeutic scaffold.

iScience · Jan 21, 2024Peer-reviewedMolecular Biology

Depolarizing GABA Transmission Restrains Activity-Dependent Glutamatergic Synapse Formation in the Developing Hippocampal Circuit

Christopher K. Salmon, Horia Pribiag, Claire Gizowski, William Todd Farmer, Scott Cameron, Emma V. Jones, Vivek Mahadevan, Charles W. Bourque, David Stellwagen, Melanie A. Woodin, Keith Kazuo Murai

This study shows that depolarizing GABAA transmission inhibits glutamatergic synapse formation in developing hippocampal neurons, with effects that persist after the transmission switches to hyperpolarizing.

Frontiers in Cellular Neuroscience · Feb 25, 2020Peer-reviewedNeuroscience