Impact of Absent in Melanoma 2 (AIM2) on Antigen-Specific CD4+ T cell Activation and Homeostasis.
Dakota M. Reinartz, Chloe Sairs, Wang Gong, Lei Ye, Michael S. Kuhns, Justin E. Wilson
This study investigates AIM2's role in CD4+ T cell activation and homeostasis, finding it promotes IL-2 production in vitro but not essential for in vivo functions like tumor control.
bioRxiv · Dec 30, 2025 · PreprintImmunology