Author

Yentli E. Soto Albrecht

Children's Hospital of PhiladelphiaORCID 0000-0002-2121-3115Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Adam D. NitidoiD· 1 shared Afshin BeheshtiiD· 1 shared Alejandro Benjamin BalazsiD· 1 shared Alessia AngeliniD· 1 shared Allen Z. LiniD· 1 shared Amanda Saravia-ButleriD· 1 shared Amarendra PeguiD· 1 shared Benjamin MooniD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Adam D. NitidoORCID

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2 papers

Recent·Most cited

HIV broadly neutralizing antibody escape dynamics drive the outcome of AAV vectored immunotherapy in humanized mice

Nicolás M. S. Gálvez, Adam D. Nitido, Seo Bin Yoo, Yi Cao, Cailin E. Deal, Christine L. Boutros, Scott W. MacDonald, Yentli E. Soto Albrecht, Evan Christopher Lam, Maegan L. Sheehan, Dylan Parsons, Allen Z. Lin, Martin J. Deymier, Jacqueline M. Brady, Benjamin Moon, , Alejandro Benjamin Balazs

This paper uses humanized mice to study how HIV resistance to broadly neutralizing antibodies (bNAbs) affects the efficacy of AAV-delivered immunotherapy, finding that escape mutation fitness costs and resistance benefits determine therapeutic success.

Immunity · Feb 25, 2026Peer-reviewedMicrobiology

Targeted Down Regulation Of Core Mitochondrial Genes During SARS-CoV-2 Infection

Joseph W. Guarnieri, Joseph M. Dybas, Hossein Fazelinia, Man Soo Kim, Justin J. Frere, Yuanchao Zhang, Yentli E. Soto Albrecht, Deborah G. Murdock, Alessia Angelin, Larry N. Singh, Scott L. Weiss, Sonja M. Best, Marie T. Lott, Henry Cope, Victoria Zaksas, , Douglas C. Wallace

This study investigates how SARS-CoV-2 infection affects mitochondrial gene expression in different tissues and disease stages, finding targeted inhibition in some organs and upregulation in others.

bioRxiv · Feb 19, 2022 · PreprintMolecular Biology