Rob J. de Boer

This paper develops a high-dimensional HIV-1 quasispecies model to predict viral rebound and guide antibody design without fitting to experimental data.

The paper develops a mathematical model to simulate phage therapy success by considering bacterial resistance dynamics and cocktail composition.

The paper introduces a simple analytical method to test structural identifiability of ordinary differential equation models by leveraging parameter scaling invariance, demonstrating its effectiveness through examples and comparisons with existing methods.

This study shows CXCL4 drives inflammation and fibrosis by altering monocyte-derived cell differentiation through transcriptional and epigenetic changes.