Author

Eric Y. Lian

University of OttawaORCID 0000-0002-2147-5422Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

William L. StanfordiD· 2 shared Adam PietroboniD· 1 shared Alberto Camacho‐Magallanes· 1 shared Alvin P. JoseliniD· 1 shared Amanda Bruce· 1 shared Arnold S. KristofiD· 1 shared Benjamin NguyeniD· 1 shared Brodie Buchner-Duby· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

William L. StanfordORCID

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2 papers

Recent·Most cited

Genome-wide functional genomics screens identify therapeutic vulnerabilities for lymphangioleiomyomatosis

Alberto Camacho‐Magallanes, Sean P. Delaney, Eric Y. Lian, Ellis Wiljer, Julien Yockell‐Lelièvre, Lisa M. Julian, Adam Pietrobon, William Batoff, Arnold S. Kristof, William L. Stanford

Differentiating TSC2-null human pluripotent stem cells into neural crest cells models lymphangioleiomyomatosis and reveals TWIST1 and SUN4 as synthetic lethal targets whose antisense knockdown eradicates mouse allograft tumors.

bioRxiv · Jul 17, 2026 · PreprintCancer Biology✦ In-depth digest

Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy

Jean-Louis A. Parmasad, Konrad M. Ricke, Benjamin Nguyen, Morgan G. Stykel, Brodie Buchner-Duby, Amanda Bruce, Haley M. Geertsma, Eric Y. Lian, Nathalie A. Lengacher, Steve M. Callaghan, Alvin P. Joselin, Julianna J. Tomlinson, Michael G. Schlossmacher, William L. Stanford, Jiyan Ma, , Maxime W.C. Rousseaux

This study shows that reducing CDK14 genetically or pharmacologically decreases alpha-synuclein pathology and improves symptoms in Parkinson's disease models.

Cell Death and Disease · Apr 4, 2024Peer-reviewedNeuroscience