CXCL16 mediates nociception and inflammation in murine post-traumatic osteoarthritis
Lindsey Lammlin, Stephen J. Redding, Alexander J. Knights, Aanya Mohan, Michael D. Newton, Rachel F. Bergman, Isabelle J. Smith, Scarlet C. Howser, Sofia Gonzalez-Nolde, Phillip Rzeczycki, Natalie S. Adamczyk, Rachel E. Miller, Tristan Maerz
This study shows CXCL16 drives synovial inflammation and joint pain through CXCR6, suggesting it as a target for treating post-traumatic osteoarthritis.
bioRxiv · Apr 10, 2025 · PreprintPhysiology