Author

Hakan Kayır

Western UniversityORCID 0000-0002-6423-4207Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:rat· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Jibran Younis KhokhariD· 4 shared Richard Quansah AmissahiD· 3 shared Abdalla M. AlbeelyiD· 2 shared Ahmad Hassan· 2 shared Jude A. FrieiD· 2 shared Abraham A. PalmeriD· 1 shared Alba Sanchis‐JuaniD· 1 shared Alex Li· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersNeuroscience

Jibran Younis KhokharORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Cannabis THC:CBD Composition Affects Oligodendrocyte Progenitor Cell Characteristics Following Acute Cannabis Vapor Inhalation in Adult Male and Female Mice

Colin J. Murray, Hayley H. A. Thorpe, Hakan Kayır, Emiko Osborne, Sean W. Foster, Sophia M. Loewen, Mika Rogers, Haley A. Vecchiarelli, Jibran Younis Khokhar, Marie‐Ève Tremblay

This study examines how different cannabis THC:CBD compositions affect oligodendrocyte progenitor cells in mice after acute vapor inhalation, finding morphological and mitochondrial changes similar to early differentiation.

bioRxiv · Sep 24, 2026 · PreprintNeuroscience

Characterizing the Effects of Chronic Cannabis Vapour Exposure and Withdrawal on Cannabinoid Triad, Somatic Signs and Behavioural Network Reorganization Adult Male Rats

Abdalla M. Albeely, Hakan Kayır, Richard Quansah Amissah, Bahar Zali, Selim Karahan, Jaiden Smith, Asim A Ibrahim, Ahmad Hassan, Sara Hussein, Jude A. Frie, Jibran Younis Khokhar

This study examines the effects of chronic cannabis vapour exposure and withdrawal on behavioural networks in rats, finding significant reorganization of behavioural dynamics.

bioRxiv · Jun 17, 2026 · PreprintNeuroscience

A simple, open-source restraint system for magnetic resonance imaging in awake rats

Richard Quansah Amissah, Mahmoud Khaled Hanafy, Hakan Kayır, Peter R. Zeman, Kyle M. Gilbert, Alex Li, Miranda Bellyou, Ashley L. Schormans, Brian Leonard Allman, Jibran Younis Khokhar

This paper introduces an open-source restraint system for awake rat fMRI that eliminates anesthesia, reducing stress and motion artifacts while enabling high-quality imaging and behavioral integration.

bioRxiv · Oct 18, 2025 · PreprintNeuroscience

Aberrant recursive splicing in a human disease locus

Philip M. Boone, Ricardo Harripaul, Rachita Yadav, Michael N. Grzybowski, Mahmoud K. Hanafy, Amanda C. Lee, Esther Y. Choi, Ryan L. Collins, Oksana Polesskaya, Nina R. Makhortova, Matthew O. Larson, Hakan Kayır, Yizhi Wang, Rodolfo A. Avila, Jude A. Frie, , Michael E. Talkowski

The paper investigates the functional role of recursive splicing in CADM2, showing that its deletion leads to altered gene expression and behavioral changes in neurodevelopmental disorders.

bioRxiv · Aug 14, 2025 · PreprintGenomics

Neural and behavioral correlates of edible cannabis-induced poisoning: characterizing a novel preclinical model

Richard Quansah Amissah, Hakan Kayır, Malik Asfandyaar Talhat, Ahmad Hassan, Yu Gu, Ron Johnson, Karolina Urban, Jibran Younis Khokhar

This study investigates the neural and behavioral effects of cannabis poisoning in rats, finding sex-dependent changes in THC levels and gamma power suppression linked to cognitive impairments.

bioRxiv · Mar 15, 2023 · PreprintNeuroscience