Author

Justin Duruanyanwu

The Pirbright InstituteORCID 0000-0002-2189-3392Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Paola CampagnoloiD· 3 shared Kevin MaringeriD· 2 shared Aitana Martin Manrique· 1 shared Berenice AlindeiD· 1 shared Clive M. GrayiD· 1 shared Daniel Matamala Luengo· 1 shared Daniel SimpkiniD· 1 shared Doty B. A. OjwachiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersMicrobiology

Paola CampagnoloORCID

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3 papers

Recent·Most cited

Pericyte dysfunction alone may be insufficient to drive tick-borne orthoflavivirus NS1-mediated microvascular permeability

Emma Brown, Justin Duruanyanwu, Paola Campagnolo, Kevin Maringer

This study investigates whether NS1 from AHFV and KFDV disrupts microvascular barrier integrity in pericyte-endothelial cell cocultures and finds that pericyte dysfunction alone is insufficient to drive NS1-mediated microvascular permeability.

bioRxiv · Jul 24, 2026 · PreprintMicrobiology

Lymphatic vessel dysfunction contributes to severe dengue pathogenesis

Fatima Abukunna, Daniel Matamala Luengo, Aitana Martin Manrique, Justin Duruanyanwu, Matthew Sherwood, Priyanka Patel, Mark J. Crabtree, Graeme M. Birdsey, Kevin Maringer, Paola Campagnolo

This study shows that DENV-2 NS1 disrupts lymphatic endothelial cell function, causing hyperpermeability and impaired lymphangiogenesis, contributing to severe dengue pathogenesis.

bioRxiv · Mar 27, 2026 · PreprintMicrobiology

Diminished placental Factor XIIIA1 expression associates with long term ART and preterm birth in pregnant people living with HIV.

Doty B. A. Ojwach, Nicola E. Annels, Sunny Sunshine, Daniel Simpkin, Justin Duruanyanwu, Tariq Webber, Berenice Alinde, Nadia M. Ikumi, Michael Z. Zulu, Hlengiwe P. Madlala, Landon Myer, Thokozile Rosemary Malaba, Marie‐Louise Newell, Paola Campagnolo, Siamon Gordon, , Fernando O. Martínez

The paper links low placental Factor XIIIA1 expression with preterm birth in pregnant people living with HIV on long-term ART, suggesting ART may disrupt placental vascularization.

bioRxiv · Oct 30, 2024 · PreprintImmunology