Nicola E. Annels

Coordinated immune architecture underlies durable survival in pancreatic cancer

This study identifies that organized tertiary lymphoid structures (TLSs) with coordinated B and T cell zoning are associated with durable survival in pancreatic cancer, contrasting with disorganized TLSs in short-term survivors.

SpatioEv: Spatial evolution of protein and morphological features reveals development dynamics of cells and spatial neighbourhoods

SpatioEv analyzes spatial data to reveal cell and neighborhood dynamics, identifying disease-specific spatial signatures and developmental trajectories in tissues.

Diminished placental Factor XIIIA1 expression associates with long term ART and preterm birth in pregnant people living with HIV.

The paper links low placental Factor XIIIA1 expression with preterm birth in pregnant people living with HIV on long-term ART, suggesting ART may disrupt placental vascularization.