Author

Sandra J. Engle

Biogen (United States)ORCID 0000-0002-2213-1584Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Alfica Sehgal· 1 shared Ali Al Abdullatif· 1 shared Alla A. SigovaiD· 1 shared Bruce Campbell· 1 shared Bryan J. MatthewsiD· 1 shared Brynn N. AkerbergiD· 1 shared Dann Huh· 1 shared David A. Bumcrot· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenomics

Alfica Sehgal

Mutual co-authors in cluster

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2 papers

Recent·Most cited

GenomicsScientific ReportsPeer-reviewedJan 25, 2024

Transcriptional characterization of iPSC-derived microglia as a model for therapeutic development in neurodegeneration

Gokul Ramaswami, Yeliz Yuva-Aydemir, Brynn N. Akerberg…·David A. Bumcrot

This study assesses iPSC-derived microglia-like cells using bulk and single-cell RNA sequencing, showing they resemble primary human microglia in gene expression and respond to LXR agonists.

14 citations

humanbulk RNA-seq

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Developmental BiologybioRxivPreprintJan 11, 2022

Ablation of SAMD1 in Mice Causes Failure of Angiogenesis, Embryonic Lethality

Bruce Campbell, Sandra J. Engle, Terence R. S. Ozolinš…·Robert J. Aiello

This study shows that SAMD1 ablation in mice leads to embryonic lethality and failure of angiogenesis, suggesting a critical role in vascular development.

2 citations

mouseexperimental assay

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