Combinational adjuvants delivered by ink-jet potentiate naked mRNA vaccines for robust protection against infectious diseases
Nan Qiao, Junichi Ishikawa, Fumihiko Yasui…·Satoshi Uchida
This study identifies a combination of adjuvants that enhance the immunogenicity of naked mRNA vaccines delivered by jet-injection, achieving protection against SARS-CoV-2 and influenza with reduced reactogenicity.