Author

Junichi Ishikawa

Innovation Center of NanoMedicinePrimary ORCID profile (0000-0001-6204-0305 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Junichi IshikawaiD1 paper · Chiba University

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:multiome· 1

Frequent Co-Authors

Kazunori KataokaiD· 2 shared Nan Qiao· 2 shared Satoshi UchidaiD· 2 shared Ahmad Faisal Amiry· 1 shared Akimasa HayashiiD· 1 shared Anjaneyulu DirisalaiD· 1 shared Bhaskar ChatterjeeiD· 1 shared Fumihiko YasuiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBioengineering

Kazunori KataokaORCID

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2 papers

Recent·Most cited

2-arm-PEG-oligocations transiently shield the liver sinusoids to mitigate off-target hepatic expression of mRNA lipid nanoparticles

Anjaneyulu Dirisala, Bhaskar Chatterjee, Le Bui Thao Nguyen, Kazuko Toh, Miki Matsui-Masai, Saed Abbasi, Xueying Liu, Theofilus A. Tockary, Nan Qiao, Junichi Ishikawa, Jumpei Norimatsu, Yuki Mochida, Shigeto Fukushima, Makoto Oba, Kazunori Kataoka, Satoshi Uchida

This paper demonstrates that 2-arm-PEG-oligocations transiently shield liver sinusoids to reduce off-target hepatic mRNA expression and improve iLNP delivery to spleen and tumors.

ACS Nano · Aug 18, 2026Peer-reviewedBioengineering

Combinational adjuvants delivered by ink-jet potentiate naked mRNA vaccines for robust protection against infectious diseases

Nan Qiao, Junichi Ishikawa, Fumihiko Yasui, Kaori Sano, Kei Miyakawa, Akimasa Hayashi, Ahmad Faisal Amiry, Liu Haonan, Zhu Xueyang, Taku Sato, Renata Pasqualini, Wadih Arap, Kazunori Kataoka, Hideki Hasegawa, Michinori Kohara, Satoshi Uchida

This study identifies a combination of adjuvants that enhance the immunogenicity of naked mRNA vaccines delivered by jet-injection, achieving protection against SARS-CoV-2 and influenza with reduced reactogenicity.

bioRxiv · Dec 27, 2025 · PreprintBioengineering