Author

Randolph J. Noelle

Dartmouth Cancer CenterORCID 0000-0002-2222-2136Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Christopher M. BurnsiD· 3 shared Elizabeth C. NowakiD· 3 shared Bruce R. BlazariD· 2 shared Janet Louise LinesiD· 2 shared Lindsay K. Mendyka· 2 shared Mohamed A. ElTanboulyiD· 2 shared Rodwell Mabaera· 2 shared Sladjana Skopelja‐GardneriD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersImmunology

Christopher M. BurnsORCID

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Author profile →

3 papers

Recent·Most cited

Keratinocyte VISTA attenuates UV light-induced skin injury by suppressing cutaneous type I interferon (IFN-I) response

Zachary T. Peters, Lindsay K. Mendyka, J'Voughnn A. Blake, Himanshu Ballav Goswami, Angelique N. Cortez, Grace E. Crossland, Sicong Shan, Elizabeth C. Nowak, Myana Keusch, Mrinal K. Sarkar, Johann Eli Gudjonsson, Christopher M. Burns, Dorothea Torti Barton, Bruce R. Blazar, Tyler Jay Curiel, , Sladjana Skopelja‐Gardner

This study identifies VISTA as a suppressor of UV-induced IFN-I responses in keratinocytes, reducing skin injury in mice and human cells.

JCI Insight · Oct 6, 2026Peer-reviewedImmunology

The role of VISTA engagement in limiting neutrophil-mediated inflammation

Elizabeth C. Nowak, Jiannan Li, Zachary T. Peters, Lindsay K. Mendyka, Mohamed A. ElTanbouly, Wilson L. Davis, Petra A. Sergent, Janet Louise Lines, Nicole C. Smits, Rodwell Mabaera, Shibani Rajanna, Catherine Carrière, Brent H. Koehn, Jeremy R. Allred, Bruce R. Blazar, , Sladjana Skopelja‐Gardner

This study shows that agonist anti-VISTA antibodies reduce neutrophil inflammation by decreasing their peripheral accumulation and increasing liver cell death, improving arthritis in mice.

The Journal of Immunology · Jun 26, 2025Peer-reviewedImmunology

Heterogeneity and plasticity of the naive CD4+ T cell compartment

Alia Sajani, Evelien Schaafsma, Walburga Croteau, Mohamed A. ElTanbouly, Elizabeth C. Nowak, Chao Cheng, Christopher M. Burns, Mary Jo Turk, Randolph J. Noelle, Janet Louise Lines

This study identifies transcriptionally distinct naive CD4+ T cell subsets in mice and humans using scRNA-seq, showing their functional diversity and environmental responsiveness.

bioRxiv · Oct 2, 2024 · PreprintImmunology