Jérôme Gros

This study investigates actin and myosin dynamics during epithelial remodeling in avian gastrulation, showing that junctional myosin contraction drives cell rearrangements and primitive streak formation.

EpiCure is a tool for curating epithelial segmentation errors in 2D movies, improving accuracy and efficiency in single-cell dynamics analysis.

The paper uses live imaging to show that avian hypoblast movement and patterning are consequences of NODAL signaling, not drivers of primitive streak induction.

The paper identifies an active torque dipole in avian embryos that drives left-right symmetry breaking through tissue rotation.

The paper measures active forces and material properties in developing quail embryos, revealing elastic and viscous behavior under active regulation and the role of cell division in tissue fluidization.

The paper investigates how tension during epiboly drives morphological changes in avian extra-embryonic cells, leading to the formation of the primitive streak.

The paper demonstrates an efficient CRISPR/Cas9 method for somatic knock-in of reporters in avian embryos, enabling dynamic monitoring of protein distribution and labeling of neural sub-populations.

The paper shows mechanical forces in avian embryos self-organize like a Turing model, guiding tissue flows and gene expression to form embryos, even under perturbations.

The paper introduces LocalZProjector and DeProj, tools for accurate 2D projection and morphometric analysis of 3D microscopy images, showing they handle complex data and correct projection distortions.

The paper presents a high-quality quail genome and uses it to study social behavior, photoperiodism, and immune response to H5N1 influenza.

The paper shows that a large-scale actomyosin ring drives tissue flows during avian gastrulation, shaping the embryo through fluid-like mechanics.

This study shows Hox genes control avian forelimb position through timed collinear activation during gastrulation and subsequent regulation of limb initiation.