Mehdi Saadaoui

The paper shows MYCN overexpression in avian embryos leads to SHH medulloblastoma-like tumors through a three-step process involving ATOH1+ progenitors and PAX6 reprogramming.

The paper introduces a two-stage framework for detecting cell divisions in 2D and 3D time-lapse images using segmentation and regression models, achieving high accuracy with efficient architectures.

This study identifies a conserved role of serotonin signaling in regulating actomyosin contractility during morphogenesis across Drosophila and chicken embryos.

The paper shows that a large-scale actomyosin ring drives tissue flows during avian gastrulation, shaping the embryo through fluid-like mechanics.