Jacqueline F. Pelham

Proteoform plasticity modulates the temperature response in circadian timekeeping

This study investigates how alternative splicing of intrinsically disordered regions in the fungal circadian protein FRQ affects temperature-dependent clock function.

Chromatin Assembly Factor 1 is required for normal structure and function of facultative heterochromatin in Neurospora crassa

This study shows that CAF-1 is necessary for proper structure and function of facultative heterochromatin in Neurospora crassa, working with PRC2 to silence transcription.

Direct prediction of intermolecular interactions driven by disordered regions

The paper develops a method to predict intermolecular interactions between intrinsically disordered regions and partner proteins using chemical physics principles.

Rhythmidia: a modern tool for circadian period analysis of filamentous fungi

Rhythmidia is a Python-based GUI tool for analyzing circadian periods and growth rates in Neurospora crassa race tube experiments, offering efficient and accurate results.

The formation of a fuzzy complex in the negative arm regulates the robustness of the circadian clock.

The paper identifies a fuzzy complex formed by negative-arm proteins that regulates the robustness of the circadian clock through electrostatic interactions and conserved motifs.

Conformational Changes in the Negative Arm of the Circadian Clock Correlate with Dynamic Interactomes Involved in Post-transcriptionally Regulated Processes

The paper investigates conformational changes in circadian clock negative arm proteins and their role in post-transcriptional regulation through dynamic interactomes.