Author

Helena Rawsthorne

University of SouthamptonORCID 0000-0002-2284-8112Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Fernando CalahorroiD· 2 shared James DilloniD· 2 shared Lindy M. Holden-DyeiD· 2 shared Vincent M. O'ConnoriD· 2 shared Emily Feist· 1 shared Patricia G. IzquierdoiD· 1 shared Philippe Tardy· 1 shared Thomas BouliniD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 25 mutual co-author links

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2 shared papersGenetics

Fernando CalahorroORCID

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2 papers

Recent·Most cited

GeneticsPLoS ONEPeer-reviewedJan 18, 2022

Confounds of using the unc-58 selection marker highlights the importance of genotyping co-CRISPR genes

Helena Rawsthorne, Fernando Calahorro, Patricia G. Izquierdo…·James Dillon

The paper demonstrates that using co-CRISPR marker genes in C. elegans can lead to hidden genomic rearrangements that affect gene function, emphasizing the need for sequencing co-CRISPR genes after CRISPR editing.

7 citations

C. elegansexperimental assay

𝕏 PostBluesky

NeuroscienceHuman Molecular GeneticsPeer-reviewedNov 1, 2020

Neuroligin dependence of social behaviour in C. elegans provides a model to investigate an autism associated gene

Helena Rawsthorne, Fernando Calahorro, Emily Feist…·James Dillon

This study investigates the role of neuroligin in social behavior in C. elegans by using CRISPR/Cas9 to edit an autism-associated mutation and shows its impact on social circuitry.

14 citations

C. elegansexperimental assay

𝕏 PostBluesky