James Dillon

This study uses C. elegans to investigate epigenetic modifiers linked to autism spectrum disorder, identifying behavioral and phenotypic changes related to sensory processing and development.

This paper identifies and characterizes an allatostatin C GPCR system in Octopus vulgaris, revealing two receptors with distinct potency in response to the same peptide.

This study identifies and functionally validates TRPV channels in Octopus vulgaris as polymodal nociceptors using in silico analysis and heterologous expression in model organisms.

The paper identifies 51 potential nociceptive genes in Octopus vulgaris using a bioinformatic pipeline and validates 18 in C. elegans through loss-of-function experiments.

The paper demonstrates that using co-CRISPR marker genes in C. elegans can lead to hidden genomic rearrangements that affect gene function, emphasizing the need for sequencing co-CRISPR genes after CRISPR editing.

This study investigates the role of neuroligin in social behavior in C. elegans by using CRISPR/Cas9 to edit an autism-associated mutation and shows its impact on social circuitry.

This study shows that C. elegans nlg-1 mutants are defective in food-induced pharyngeal pumping, despite normal chemotaxis, suggesting neuroligin regulates feeding circuits outside the pharynx.