ImmunologybioRxivPreprint
BCL11B targeting in tumor CD8+ T cells amplifies anti-tumor response by blocking exhaustion while promoting stemness and cytotoxicity
Leonardo Silvane, Τόμας Ζελένκα, Divya Priyanka Talada…·Dorina Avram
This paper shows that reducing BCL11B in CD8+ T cells enhances anti-tumor response by preventing exhaustion and boosting stemness and cytotoxicity.