Author

Juan Shen

Centre for Human GeneticsORCID 0000-0002-2344-1971Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Juan Shen1 paper · University of Oxford

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Long CheniD· 2 shared Peijun ZhangiD· 2 shared Yao SheniD· 2 shared Alex B. KleinpeteriD· 1 shared Anka Lucic· 1 shared David Ian StuartiD· 1 shared Eric O. FreediD· 1 shared Jialu XuiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMicrobiology

Long ChenORCID

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2 papers

Recent·Most cited

In situ chromatin dynamics and HIV-1 nuclear trafficking

Zhen Hou, Yao Shen, Long Chen, Juan Shen, David Ian Stuart, Peijun Zhang

This study visualizes chromatin structure and HIV-1 nuclear trafficking in situ, showing HIV-1 cores preferentially associate with open chromatin and are excluded from compact regions.

bioRxiv · Jan 9, 2026 · PreprintMicrobiology

Structural basis for HIV-1 capsid adaption to rescue IP6-packaging deficiency

Yanan Zhu, Alex B. Kleinpeter, Juan S. Rey, Juan Shen, Yao Shen, Jialu Xu, Nathan J. Hardenbrook, Long Chen, Anka Lucic, Juan R. Perilla, Eric O. Freed, Peijun Zhang

This paper identifies a mutation, G225R, that restores capsid formation and infectivity to HIV-1 mutants deficient in IP6 packaging by stabilizing the capsid structure in low-IP6 conditions.

bioRxiv · Feb 9, 2025 · PreprintMicrobiology