Fan Liu

This study identifies an antagonistic interaction between Spinophilin and Syd-1 that regulates presynaptic long-term plasticity and olfactory memory in Drosophila.

The paper improves inter-link detection in cross-linking mass spectrometry by using a fused database and context-sensitive subgrouping, increasing coverage by 30-75% while maintaining low error rates.

The paper introduces real-time library search (RTLS) to improve cross-link identification in XL-MS by leveraging intensity ratios of diagnostic peaks, enhancing identification depth in complex samples.

XlinkCyNET is a Cytoscape plugin for visualizing protein interaction networks derived from cross-linking mass spectrometry data.

This paper summarizes current XL-MS practices, compares strategies, and proposes common protocols to establish best practice guidelines for accurate and reproducible results.