Shigenobu Yonemura

Genome-edited retinal organoids restore host bipolar connectivity in the primate macula

This study transplants genome-edited retinal organoids into a primate macular degeneration model, showing host bipolar cells rewire and form functional synapses with grafted photoreceptors.

Myosin cluster dynamics determines epithelial wound ring constriction

The paper shows that myosin cluster dynamics in multi-cellular epithelial wound rings are conserved with single-cell cytokinetic rings and can predict stress generation and shape changes during morphogenesis.

Nanopore formation in the cuticle of an insect olfactory sensillum

The paper identifies an insect-specific endosomal protein involved in forming nanopores in the cuticle, essential for odor detection.

Hair Follicle Epidermal Stem Cells Define a Niche for Tactile Sensation

The paper identifies a niche of hair follicle epidermal stem cells that support tactile sensation by maintaining stable interfaces with mechanosensory structures.