Richard D. Smith

This paper introduces a method for label-free single voxel proteomics using wcSOP, enabling spatial resolution of protein expression in tissue samples.

The paper compares cerebrospinal fluid proteomes of ME/CFS patients with and without fibromyalgia, finding no significant differences, suggesting they may not be distinct conditions.

This paper introduces TIFF, a method enhancing single-cell proteomics sensitivity and accuracy by filtering background ions and using 3D MS1 feature matching, achieving deep proteome analysis in single cells.

This paper introduces a nested nanowell chip to improve single-cell proteomics throughput and robustness, demonstrating the ability to quantify ~1500 proteins from ~100 cells with low abundance variation.

This study uses lipidomics to analyze leaf-cutter ant fungal gardens, showing lipids play roles in energy transfer and inter-kingdom communication through differential fatty acid responses.