Author

Emily Da Cruz

Harvard UniversityORCID 0000-0002-2402-9014Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Aarushi Gandhi· 1 shared Angelyna Siv· 1 shared Benjamin Ondeck· 1 shared C.K. Fong· 1 shared Cenk AyataiD· 1 shared David HikeiD· 1 shared David Y. ChungiD· 1 shared Diana TambalaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPhysiology

Aarushi Gandhi

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1 paper

Recent·Most cited

Smooth Muscle Dysfunction Drives Cerebrovascular Reserve Failure and End-Organ Brain Injury

Takahiko Imai, Vijai Krishnan, James Han Lai, Elyssa Alber, Lydia Hawley, Aarushi Gandhi, Pazhanichamy Kalailingam, Joanna Yang, Diana Tambala, David Hike, Xiaoqing Alice Zhou, C.K. Fong, Benjamin Ondeck, Emily Da Cruz, Xiaochen Liu, , David Y. Chung

This study shows that smooth muscle dysfunction caused by ACTA2 mutations leads to cerebrovascular reserve failure, increasing brain vulnerability to hypoperfusion and injury.

bioRxiv · Jan 26, 2026 · PreprintPhysiology