Mechanism-based prediction of insertion-driven high pathogenicity avian influenza virus emergence
Gabriel Dupré, Bertille Pouget, Aldair Martin Martínez Pineda, Charlotte Foret, Pierre Bessière, Delphine Chrétien, Mariette F. Ducatez, Nathalie Vialaneix, Claire Hoede, Roland Marquet, Christine Gaspin, Romain Volmer
This study identifies the molecular mechanism of insertion-driven HPAIV emergence and introduces a predictive tool to identify predisposed HA sequences.
bioRxiv · Sep 1, 2026 · PreprintMicrobiology