Intrinsically disordered RNA-binding motifs cooperate to catalyze RNA folding and drive phase separation
Annika Niedner, Thomas Monecke, Janosch Hennig, Melina Klostermann, Mario Hofweber, Elena Davydova, André P. Gerber, Irina Anosova, Wieland Mayer, Marisa Müller, Roland G. Heym, Robert Janowski, Jean‐Christophe Paillart, Dorothee Dormann, Kathi Zarnack, , Dierk Niessing
This study identifies PUN motifs in yeast Loc1p that cooperate to catalyze RNA folding and drive phase separation, suggesting a role in RNA and DNA-related processes across species.
Nucleic Acids Research · Nov 15, 2024Peer-reviewedBiochemistry