Author

Daria Esterházy

University of ChicagoORCID 0000-0002-2427-9873Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Macy R. KomnickiD· 3 shared Emily Schaffer· 2 shared Gwen M. TayloriD· 2 shared Hailey M. BrowniD· 2 shared Kay L. FiskeiD· 2 shared Terence S. DermodyiD· 2 shared Yixuan D. Zhou· 2 shared Alexander MuiriD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersImmunology

Macy R. KomnickORCID

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3 papers

Recent·Most cited

T cell fate is dictated by different antigen presenting cells in response to dietary versus gut epithelial self-antigen

Yixuan D. Zhou, Hailey M. Brown, Emily Schaffer, Gwen M. Taylor, Kay L. Fiske, Macy R. Komnick, Sebastian Lopez, Terence S. Dermody, Daria Esterházy

The paper shows that T cell fate differs based on antigen source and APC type, with distinct outcomes for dietary versus epithelial antigens.

Immunity · Aug 26, 2026Peer-reviewedImmunology

Tissue-specific tolerance mechanisms and lymph node co-drainage converge to shape T cell immunity in the upper digestive system and regulate pancreatic cancer progression

Yixuan D. Zhou, Z. Peter Wang, Emily Schaffer, Macy R. Komnick, Hailey M. Brown, Gwen M. Taylor, Kay L. Fiske, Colin S. Sheehan, Terence S. Dermody, Alexander Muir, Daria Esterházy

bioRxiv · Dec 5, 2025 · PreprintImmunology

Inducible, but not constitutive, pancreatic REG/Reg isoforms are regulated by intestinal microbiota and pancreatic diseases

Yixuan Zhou, Macy R. Komnick, Fabiola Sepulveda, Grace Liu, Elida Nieves-Ortiz, Kelsey Meador, Ornella Ndatabaye, Aliia R. Fatkhullina, Asha J. Bozicevich, Braden Juengel, Natalie J. Wu-Woods, Paulina M. Naydenkov, Johnathan R. Kent, Nathaniel Christiansen, Maria Lucia L. Madariaga, , Daria Esterházy

The paper investigates differences in REG/Reg isoform expression and regulation in pancreas and gut, finding inducible isoforms are regulated by microbiota and pancreatic diseases.

Mucosal Immunology · May 19, 2025Peer-reviewedImmunology