Z. Peter Wang

Patchouli alcohol suppresses gastric cancer growth and immune evasion via inhibition of the NF-κB/PD-L1 axis

This study shows that Patchouli alcohol inhibits gastric cancer growth and immune evasion by suppressing the NF-κB/PD-L1 axis, enhancing T-cell cytotoxicity.

Tissue-specific tolerance mechanisms and lymph node co-drainage converge to shape T cell immunity in the upper digestive system and regulate pancreatic cancer progression

Directed evolution of a compact TranC11a system for efficient genome editing

This study evolves the TranC11a system to improve genome editing efficiency in human and plant cells, achieving performance comparable to SpCas9.

Intratumor Heterogeneity and Evolution of Colorectal Cancer

This study examines intratumor heterogeneity and evolution patterns in colorectal cancer, finding a Darwinian pattern with differences between right-sided and left-sided tumors.