Thomas J. Park

Comparative analysis of naked mole-rat thermogenesis and its potential to maintain euthermia in response to cold

This study investigates the thermogenic potential of naked mole-rat brown adipose tissue and its ability to maintain body temperature in cold, finding that NMRs can initiate non-shivering thermogenesis but cannot sustain it due to heat loss and substrate limitations.

ULK1-linked mitophagy promotes cardiac hypoxia tolerance in the blind mole-rat

This study identifies ULK1-linked mitophagy as a mechanism enabling cardiac hypoxia tolerance in blind mole-rats through metabolic and mitochondrial adaptations.

Sociality shapes mitochondrial adaptations supporting hypoxia tolerance

This study identifies mitochondrial adaptations in naked mole-rats that confer hypoxia resistance, linking social behavior to molecular evolution.

Phylogenetic modeling of enhancer shifts in African mole-rats reveals regulatory changes associated with tissue-specific traits

The paper uses phylogenetic modeling to analyze epigenomic changes in mole-rats and identifies regulatory elements associated with metabolic and hypoxia-related traits.