Author

Kai Breuhahn

German Cancer Research CenterORCID 0000-0002-2462-1229Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Peter SchirmacheriD· 2 shared Ahmed GhallabiD· 1 shared Christos Patsis· 1 shared Darjus Felix TschaharganehiD· 1 shared Hendrik WiethoffiD· 1 shared Ilse HofmanniD· 1 shared Jan Georg HengstleriD· 1 shared Jennifer Schmitt· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Peter SchirmacherORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 17, 2025

Repurposing passenger amplifications as Trojan horses identifies MPZL1 as a potent target for solid cancers

Sonia Jiménez Vázquez, Christos Patsis, Mara Mitstorfer…·Darjus Felix Tschaharganeh

The paper identifies MPZL1 as a therapeutic target in 1q-amplified solid cancers by repurposing passenger amplifications as Trojan horses for targeted therapy delivery.

DOI 10.1101/2025.09.17.675062

humanproteomics

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Molecular BiologyeLifePeer-reviewedSep 22, 2022

Spatial modeling reveals nuclear phosphorylation and subcellular shuttling of YAP upon drug-induced liver injury

Lilija Wehling, Liam Keegan, Paula Fernández‐Palanca…·Kai Breuhahn

The paper uses PDE modeling and image analysis to show that nuclear phosphorylation and AKT interaction regulate YAP and TAZ shuttling dynamics in response to APAP-induced liver injury.

14 citations

mouseimaging

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