Author

Senthil Damodaran

The University of Texas MD Anderson Cancer CenterORCID 0000-0002-2470-0891Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Assay:multiome· 1 Assay:proteomics· 1

Frequent Co-Authors

Aislyn P. SchalckiD· 1 shared Alaina N. LewisiD· 1 shared Alana L. WelmiD· 1 shared Alejandro ContrerasiD· 1 shared Alexander B. SaltzmaniD· 1 shared Alexander DavisiD· 1 shared Anna MalovannayaiD· 1 shared Antrix JainiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenomics

Aislyn P. SchalckORCID

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2 papers

Recent·Most cited

Patient-Derived Xenograft-Guided Prediction of Chemotherapy Response in Triple-Negative Breast Cancer

Jonathan Thomas Lei, Lacey Elizabeth Dobrolecki, Chen Lu Huang, Ramakrishnan Rajaram Srinivasan, Suhas V. Vasaikar, Alaina N. Lewis, Christina Sallas, Na Zhao, Jin Cao, John David Landua, Jacob B. Pilcher, Chang In Moon, Yuxing Liao, Susan Galloway Hilsenbeck, Mothaffar Fahed Rimawi, , Michael T. Lewis

This paper develops chemotherapy-specific predictors for triple-negative breast cancer using patient-derived xenografts and multi-omic data, achieving high AUROC scores for response prediction.

bioRxiv · Dec 9, 2024 · PreprintCancer Biology

Resolving clonal substructure from single cell genomic data using CopyKit

Darlan Conterno Minussi, Emi Sei, Junke Wang, Aislyn P. Schalck, Yun Yan, Alexander Davis, Hua‐Jun Wu, Shanshan Bai, Cheng Peng, Min Hu, Tod D. Casasent, Alejandro Contreras, Hui Chen, David Hui, Senthil Damodaran, , Nicholas E. Navin

CopyKit is a computational tool that resolves clonal substructure and reconstructs genetic lineages in tumors using single cell copy number data.

bioRxiv · Mar 9, 2022 · PreprintGenomics