Author

Yumi Yamashita-Kanemaru

University of CambridgeORCID 0000-0002-2475-8858Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

Bidesh MahataiD· 3 shared Hosni A. M. HusseiniD· 3 shared Jhuma PramanikiD· 3 shared Natalie Z M HomeriD· 3 shared Rahul RoychoudhuriiD· 3 shared Klaus OkkenhaugiD· 2 shared Qiuchen ZhaoiD· 2 shared Sanu Korumadathil ShajiiD· 2 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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3 shared papersImmunology

Bidesh MahataORCID

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Author profile →

3 papers

Recent·Most cited

Local glucocorticoid signalling promotes pancreatic cancer

Clara Veiga-Villauriz, Hosni A. M. Hussein, Christopher J. Ward, Sanu K. Saji, Soura Chakraborty, Jhuma Pramanik, Yumi Yamashita-Kanemaru, Joanna P. Simpson, Sofia Laforest, Federico Diez, Natalie Z M Homer, Rahul Roychoudhuri, Timotheus Y.F. Halim, Bidesh Mahata

This study identifies Hsd11b1 as a key enzyme promoting glucocorticoid signaling in pancreatic cancer, contributing to immunosuppression and fibrosis, suggesting HSD11B1 as a therapeutic target.

bioRxiv · Nov 14, 2025 · PreprintCancer Biology

Drug repurposing reveals Posaconazole as a CYP11A1 inhibitor enhancing anti-tumour immunity

Jhuma Pramanik, Sanu Korumadathil Shaji, Megan Zaman, Bethany Brown, Baojie Zhang, Yumi Yamashita-Kanemaru, Natalie Z M Homer, Hosni A. M. Hussein, Qiuchen Zhao, Klaus Okkenhaug, Rahul Roychoudhuri, Abhik Mukhopadhyay, Bidesh Mahata

The paper identifies Posaconazole as a CYP11A1 inhibitor that enhances anti-tumour immunity in a mouse model of lung metastasis.

iScience · Apr 18, 2025Peer-reviewedImmunology

Primitive steroidogenesis in mast cells: A novel regulatory mechanism for mast cell function

Jhuma Pramanik, Qiuchen Zhao, Yumi Yamashita-Kanemaru, Hosni A. M. Hussein, Natalie Z M Homer, Soura Chakraborty, Sanu Korumadathil Shaji, Klaus Okkenhaug, Rahul Roychoudhuri, Bidesh Mahata

This study identifies de novo steroidogenesis in mast cells as a novel regulatory mechanism essential for their development, survival, and function, with implications for inflammatory and anaphylactic responses.

bioRxiv · Feb 5, 2025 · PreprintImmunology