Author

Ke Wu

Gladstone InstitutesORCID 0000-0002-7463-1185Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

Megan S OstrowskiiD· 2 shared Abigail E. HeiniD· 1 shared Bao ThaiiD· 1 shared Camille M. MooreiD· 1 shared Emily V. WongiD· 1 shared Geeta J. NarlikariD· 1 shared Iryna IrkliyenkoiD· 1 shared Samentha Kwok· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

Megan S OstrowskiORCID

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2 papers

Recent·Most cited

ATP-dependent remodeling of chromatin condensates uncovers distinct mesoscale effects of two remodelers

Camille M. Moore, Emily V. Wong, Upneet Kaur, U. S. M. Chio, Ziling Zhou, Megan S Ostrowski, Ke Wu, Iryna Irkliyenko, Simai Wang, Vijay Ramani, Geeta J. Narlikar

The paper investigates how two chromatin remodelers, ACF and RSC, affect chromatin condensation and dynamics, revealing distinct mesoscale effects on chromatin structure and function.

Science · Oct 2, 2025Peer-reviewedBiochemistry

Single molecule co-occupancy of RNA-binding proteins with an evolved RNA deaminase

Yizhu Lin, Samentha Kwok, Abigail E. Hein, Bao Thai, Yewande Alabi, Megan S Ostrowski, Ke Wu, Stephen N. Floor

The paper introduces REMORA, a method to record RNA-protein interactions on single RNA molecules by using RNA deaminases, and shows competition between PUM1 and PUM2 for RNA binding sites.

Nature Methods · Oct 19, 2023Peer-reviewedMolecular Biology