Guofang Zhang

This study integrates multi-omics data from alcohol-fed mice to reveal metabolic and epigenetic changes in early alcohol-associated liver disease, highlighting a shift toward antioxidant responses.

This study integrates transcriptomic and metabolomic analyses to reveal novel regulatory functions of ChREBP in mitochondrial metabolism and cellular energy balance beyond its canonical roles in carbohydrate and lipid metabolism.

This study identifies CoA-mediated post-translational modification of TXNRD2 as a novel mechanism regulating the mitochondrial thioredoxin system to protect against ferroptosis.