Differential Effects of 5-HT7 Receptor Signaling in the Noradrenergic System in a Rat Model of Treatment-Resistant Depression
Cristina Bruzos-Cidón, Nerea Llamosas, Harkaitz Bengoetxea, José Vicente Lafuente, Luisa Ugedo, Marı́a Torrecilla
This study investigates the effects of 5-HT7 receptor activation on locus coeruleus function in a rat model of treatment-resistant depression, finding strain-dependent responses and altered receptor expression.
bioRxiv · Jan 5, 2026 · PreprintNeuroscience