NeuroscienceJournal of NeurosciencePeer-reviewed
Notch inhibition promotes regeneration and immunosuppression supports cone survival in a zebrafish model of inherited retinal dystrophy
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Cleveland ClinicORCID 0000-0002-1680-8659Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Nerea Llamosas, Vineet Arora, Ridhima Vij…·Gavin Rumbaugh
This study shows that SYNGAP1 loss-of-function in human neurons leads to enhanced dendritic morphogenesis, increased excitatory synapses, and altered network activity.
Murat Kılınç, Thomas K. Creson, Camilo Rojas…·Gavin Rumbaugh
The paper investigates how the SynGAP-1 PBM regulates NMDA receptor signaling and cognitive function in mice, finding that disrupting the PBM leads to synaptic and cognitive impairments.