Min Zhao

Computational insights on the competition between electrotaxis and durotaxis

The paper investigates how electric and mechanical signals interact in cell migration, showing electric fields can override mechanical cues and proposes a platform to predict these interactions.

Development of a wireless bioelectronic actuator for wound healing in a porcine model

This paper develops a wireless bioelectronic actuator for wound healing in pigs, showing reduced M1/M2 macrophage ratio and increased re-epithelialization in treated wounds.

A Practical and Safe Model of Nitrogen Mustard Injury in Cornea

This paper introduces a safe and practical model using mechlorethamine gel to study sulfur mustard-induced corneal injuries in ex vivo porcine corneas.

Oxygen uptake in human donor corneas: the centripetal gradient and its changes in culture and correlation with wounds and aminophylline treatment

The paper characterizes the centripetal oxygen uptake gradient in human donor corneas and shows its conservation across species, changes in culture, and correlation with wound healing and aminophylline treatment.

Electric fields trigger ceramide-dependent budding of exosome vesicles into multivesicular endosomes and boost the generation of exosomes

This paper shows electric fields boost exosome production by 100-fold through ceramide-dependent mechanisms, offering a new method for exosome generation.

Galvanotactic directionality of cell groups depends on group size

This study shows that galvanotactic directionality of cell groups depends on group size and internal cell signaling, with small PI3K-inhibited groups moving to the anode and larger ones to the cathode.

Remote-Controlled Wireless Bioelectronics for Fluoxetine Therapy to Promote Wound Healing in a Porcine Model

This paper develops a remote-controlled wireless bioelectronic system for delivering fluoxetine to promote wound healing in pigs, showing improved re-epithelialization and reduced inflammation.

Competing signaling pathways controls electrotaxis

This study develops a mechanistic model to explain electrotaxis by showing how charged membrane receptors polarize and control actomyosin dynamics across cell types.

Rat primary cortical cell tri-culture to study effects of amyloid-beta on microglia function

This study uses a rat primary cortical tri-culture model to show that microglia in co-culture with neurons and astrocytes more effectively clear amyloid-beta and exhibit altered motility compared to co-culture or mono-culture.

Quantifying innervation facilitated by deep learning in wound healing

This study uses deep learning to quantify innervation changes during wound healing in mice, finding a strong correlation between nerve fiber density and re-epithelization.