Bruce W. Draper

Galvanotactic directionality of cell groups depends on group size

This study shows that galvanotactic directionality of cell groups depends on group size and internal cell signaling, with small PI3K-inhibited groups moving to the anode and larger ones to the cathode.

Multiple Wnt signaling pathways direct epithelial tubule interconnection in the regenerating zebrafish kidney

This study identifies the roles of canonical and non-canonical Wnt signaling pathways in directing epithelial tubule interconnection during zebrafish kidney regeneration.

Zebrafish lack a strong meiotic checkpoint response to defects in chromosome synapsis

This study shows zebrafish lack a strong meiotic checkpoint response to synapsis defects, leading to aneuploidy in offspring, unlike mammals and nematodes.

Rbpms2 promotes female fate upstream of the nutrient sensing Gator2 complex component, Mios

The paper identifies Rbpms2 as a regulator of oocyte fate by repressing testis factors and promoting oocyte factors through the Gator2 complex in zebrafish.

Macrophage activation drives ovarian failure and masculization

The paper identifies a macrophage-germline-somatic gonadal cell axis driven by BMP15 mutation that contributes to ovarian failure and masculization in zebrafish.

Single-cell transcriptome reveals insights into the development and function of the zebrafish ovary

The paper uses single-cell RNA sequencing to analyze zebrafish ovarian cells, identifying novel cell subpopulations and gene functions involved in ovarian development.

Rad21l1 cohesin subunit is dispensable for spermatogenesis but not oogenesis in zebrafish

This paper shows that Rad21l1 is essential for female meiosis but not male meiosis in zebrafish, leading to sex reversal and reproductive defects in females.

Reduced Fgf signaling during early zebrafish development causes ciliopathy-associated phenotypes

The paper identifies a role for FGF signaling in balancing polycystin and urotensin pathways to achieve a straight body axis in zebrafish.

Fibroblast growth factor receptors function redundantly during zebrafish embryonic development

The paper analyzes fibroblast growth factor receptor mutants in zebrafish, revealing functional redundancy that ensures robustness in developmental signaling.

The roles of Amh in zebrafish gonad development and sex determination

This study investigates the role of Amh in zebrafish gonad development and sex determination by generating amh null mutants, revealing its involvement in germ cell regulation and gonadal soma development.

The telomere bouquet is a hub where meiotic double-strand breaks, synapsis, and stable homolog juxtaposition are coordinated in the zebrafish, Danio rerio

This paper investigates the telomere bouquet in zebrafish meiosis, showing it coordinates synapsis, DSB formation, and homolog juxtaposition, with sex-specific effects of spo11 deletion on fertility.

wnt4a Promotes Female Development and Reproductive Duct Elongation in Zebrafish

This paper shows that wnt4a promotes female sex determination and reproductive duct development in zebrafish, similar to its role in mammals.