Leonard C. Harrison

The molecular basis of immunosuppression by soluble CD52 is defined by interactions of N-linked and O-linked glycans with HMGB1 Box B

This paper characterizes the glycosylation of soluble CD52 and identifies its role in immune suppression through interactions with HMGB1 and SIGLEC-10.

Functional analysis of Mmd2 and related PAQR genes during sex determination in mice

The paper investigates the role of Mmd2 and related PAQR genes in mouse sex determination, finding no essential function despite their expression in testis development.

Activation-induced re-organization of chromatin in human T cells

This study examines how T cell activation alters chromatin structure and gene expression, identifying changes in chromatin interactions and domain organization.

No kissing in the nucleus: Unbiased analysis reveals no evidence of trans chromosomal regulation of mammalian immune development

The paper uses high-resolution genome-wide chromosome conformation capture to analyze transchromosomal interactions in immune cells and finds no evidence of gene regulatory transchromosomal interactions.

Influence of fecal collection conditions and 16S rRNA gene sequencing protocols at two centers on human gut microbiota analysis

This study evaluates how fecal collection conditions and 16S rRNA sequencing protocols affect gut microbiome analysis across two centers, finding that center-specific differences outweigh collection method variations.