Author

Päivi Liisa Piirilä

University of HelsinkiORCID 0000-0002-2535-4409Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Assay:proteomics· 1

Frequent Co-Authors

Adam Philip SharplesiD· 2 shared Aino HeikkineniD· 2 shared Kirsi Hannele PietiläineniD· 2 shared Larisa Margaret HauptiD· 2 shared Lyn Robyn GriffithsiD· 2 shared Macsue JacquesiD· 2 shared Miina OllikaineniD· 2 shared Nicholas R. HarveyiD· 2 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Adam Philip SharplesORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Molecular Landscape of Modality-Specific Exercise Adaptation in Human Skeletal Muscle through Large-Scale Multi-OMICs Integration

Macsue Jacques, Shanie Landen, Adam Philip Sharples, ANDREW P. GARNHAM, Ralf B. Schittenhelm, Joel Stele, Aino Heikkinen, Elina Sillanpää, Miina Ollikainen, James R. Broatch, Navabeh Zarekookandeh, Ola Hanson, Ola Ekström, Olof Asplund, Séverine Lamon, , Nir Eynon

This study integrates multi-OMIC data from 12 cohorts to identify exercise-specific molecular signatures and gene regulatory patterns in human skeletal muscle.

bioRxiv · Jul 14, 2024 · PreprintMolecular Biology

Exercise is associated with younger methylome and transcriptome profiles in human skeletal muscle

Sarah Amandine Caroline Voisin, Kirsten Seale, Macsue Jacques, Shanie Landen, Nicholas R. Harvey, Larisa Margaret Haupt, Lyn Robyn Griffiths, Kevin J. Ashton, Vernon G. Coffey, Jamie‐Lee M. Thompson, Thomas M. Doering, Maléne E. Lindholm, Colum P. Walsh, Gareth W. Davison, Rachelle E Irwin, , Nir Eynon

This study shows exercise training reduces epigenetic and transcriptomic aging in human skeletal muscle, while muscle disuse accelerates transcriptomic aging.

Aging Cell · May 2, 2023Peer-reviewedMolecular Biology