Author

Lena Hochrein

University of PotsdamORCID 0000-0002-2548-4318Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:variant calling· 2 Organism:yeast· 2 Research Focus:genome assembly· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Adán Andrés Ramírez RojasiD· 1 shared Ali Tafazoli YazdiiD· 1 shared Cedric K. BrinkmanniD· 1 shared Ciaran RuehmkorffiD· 1 shared Daniel SchindleriD· 1 shared Karina SchulziD· 1 shared María del Carmen Sánchez OlmosiD· 1 shared Timon A. LindeboomiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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1 shared paperSynthetic Biology

Adán Andrés Ramírez RojasORCID

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2 papers

Recent·Most cited

Synthetic BiologyNucleic Acids ResearchPeer-reviewedSep 5, 2025

In Vivo Pathway Optimization in Yeast via LoxPsym-Mediated Shuffling of Upstream Activating Sequences

Ciaran Ruehmkorff, Ali Tafazoli Yazdi, Lena Hochrein

The paper introduces PULSE, a method for in vivo promoter engineering in yeast to optimize biosynthetic pathways, achieving an eightfold increase in β-carotene production and improved growth on high xylose concentrations.

1 citation

yeastexperimental assay

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Synthetic BiologyACS Synthetic BiologyPeer-reviewedApr 10, 2024

L-SCRaMbLE creates large-scale genome rearrangements in synthetic Sc2.0 chromosomes

Timon A. Lindeboom, María del Carmen Sánchez Olmos, Karina Schulz…·Daniel Schindler

The paper demonstrates the use of L-SCRaMbLE to generate large-scale genome rearrangements in synthetic Sc2.0 yeast chromosomes through light-inducible Cre recombinase.

6 citations

yeastwhole-genome sequencing

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