Noriko Saitoh

Repeat element-anchored enhancer-promoter interactions (REEPIs) shape the regulatory landscape of hormone-resistant breast cancer

The paper identifies repeat element-anchored enhancer-promoter interactions (REEPIs) in hormone-resistant breast cancer and links them to transcriptional adaptation and regulatory reprogramming.

Condensin II collaborates with cohesin to establish and maintain interphase chromosome territories

This study shows condensin II and cohesin work together to form and maintain chromosome territories during interphase, with distinct roles in different cell cycle stages.

Breast cancer identity is defined by specialized enhancer sets via lysine deacetylation

The paper identifies hypoacetylation-defined enhancers in luminal breast cancer cells and links them to subtype-specific gene regulation and patient classification.

Modeling population size independent tissue epigenomes by ChIL-seq with single-thin sections

The paper introduces tsChIL, a method to analyze tissue-level epigenomic data from single-thin sections, enabling independent evaluation of cell population changes and gene activation in regenerating skeletal muscle.

Importin α2 association with chromatin: Direct DNA binding via a novel DNA binding domain

The paper identifies a novel DNA-binding domain in importin α2 that enables chromatin association, revealing its dual role in nuclear transport and gene regulation.

Genome-wide analysis of transcriptional bursting-induced noise in mammalian cells

This study investigates transcriptional bursting kinetics in mESCs using scRNA-seq and identifies regulatory factors and pathways influencing gene expression noise.