Akatsuki Kimura

The paper shows that anisotropic lateral surface tension, mediated by HMR-1/E-cadherin, directs invagination in C. elegans gastrulation, complementing apical constriction.

This paper introduces a data-driven correction framework to account for axial- and radial-position-dependent intensity attenuation in 3D fluorescence microscopy of C. elegans embryos, improving quantitative accuracy.

The paper measures cytoplasmic mechanics in C. elegans embryos and finds a progressive stiffening that persists despite inhibited cytokinesis.

The paper simulates cytokinesis by modeling cytoplasmic flow and cortical elasticity interactions, showing spindle-driven flow creates a pressure minimum that initiates cleavage furrow formation.

This study shows condensin II and cohesin work together to form and maintain chromosome territories during interphase, with distinct roles in different cell cycle stages.

This study shows that cytoplasmic actomyosin fluctuations enhance dynein-driven transport in C. elegans embryos by accelerating motor-cargo movement through asymmetric force responses.

This study shows that constitutively active RAS in fission yeast prolongs Cdc42 signaling while reducing MAPK signaling through competitive binding and feedback mechanisms.

The paper measures cellular forces for nuclear centration in C. elegans embryos using centrifugation and microscopy, finding forces increase linearly with distance and friction is reduced in microtubule mutants.

The paper shows that cytoplasmic streaming in C. elegans zygotes dynamically positions the SPCC, determining the anterior-posterior axis through stochastic movement.

This study develops a microinjection method for C. elegans embryos using an uncoated glass needle, enabling lineage tracking and revealing cell-non-autonomous adhesion control.